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[[Image:idaho.jpg|thumb|right|700px|The University of Idaho NIML is located in Moscow, ID within the beautiful Palouse hills of the inland northwest!]]
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[[Image:idaho.jpg|thumb|right|400px|The University of Idaho NIML is located in Moscow, ID within the beautiful Palouse hills of the inland northwest!]]
{{#ev:youtube|https://youtu.be/5f46ImO1lGQ|480|left|Computer simulation of intrathecal drug dispersion in the cervical spine of a nonhuman primate |frame}}
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{{#ev:youtube|https://www.youtube.com/watch?v=KHqtsRuHTIk|400|right|MRI-based CFD simulation of CSF flow in a Chiari malformation patient by [[Soroush Pahlavian]]. |frame}}
{{#ev:youtube|https://youtu.be/oUc2tKH9InU |480|inline|A nonuniform deforming mesh simulation of cerebrospinal fluid flow in a non-human primate |frame}}
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{{#ev:youtube|https://youtu.be/5f46ImO1lGQ|400|right|Computer simulation of intrathecal drug dispersion in the cervical spine of a nonhuman primate by [[Mohammadreza Khani]]. |frame}}
{{#ev:youtube|https://www.youtube.com/watch?v=KHqtsRuHTIk|400|right|MRI-based CFD simulation of CSF flow in a Chiari malformation patient |frame}}
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{{#ev:youtube|https://youtu.be/oUc2tKH9InU |400|right|A nonuniform deforming mesh simulation of cerebrospinal fluid flow in a non-human primate by [[Mohammadreza Khani]]. |frame}}
<!-- [[Image:projects.jpg|thumb|right|400px|Ongoing research projects at the Neurophysiological Imaging and Modeling Laboratory (NIML).]] -->
 
 
[[Image:fibers.jpg|thumb|right|400px|Visualization of arachnoid trabeculae fibers with second harmonic generation (SHG), bright field and fluorescence with DAPI stain.]]
 
[[Image:fibers.jpg|thumb|right|400px|Visualization of arachnoid trabeculae fibers with second harmonic generation (SHG), bright field and fluorescence with DAPI stain.]]
<!-- [[Image:pulsatile.jpg|thumb|right|400px|Pulsatile movement of cerebrospinal fluid around the spinal cord at the second cervical vertebrae level in a healthy young subject image by [[Adrien Demuralt]].]]-->
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{{#ev:youtube|https://www.youtube.com/watch?v=j6HjqMGuSjk|400|right|Pulsatile movement of cerebrospinal fluid around the spinal cord measured in an in vitro flow model by 4D Flow MRI. |frame}}
 
{{#ev:youtube|https://www.youtube.com/watch?v=j6HjqMGuSjk|400|right|Pulsatile movement of cerebrospinal fluid around the spinal cord measured in an in vitro flow model by 4D Flow MRI. |frame}}
 
[[Image:cfd.jpg|thumb|right|400px|Computational fluid dynamics simulation of CSF movement in the cervical spine by [[Soroush Pahlavian]] with spinal cord nerve roots and denticulate ligaments included.]]
 
[[Image:cfd.jpg|thumb|right|400px|Computational fluid dynamics simulation of CSF movement in the cervical spine by [[Soroush Pahlavian]] with spinal cord nerve roots and denticulate ligaments included.]]
 
[[Image:3dprinteye.jpg|thumb|right|400px|3D printed eyeball and ocular nerve by [[Lucas Sass]] and [[Joshua Pluid]].]]
 
[[Image:3dprinteye.jpg|thumb|right|400px|3D printed eyeball and ocular nerve by [[Lucas Sass]] and [[Joshua Pluid]].]]
<!-- [[Image:4DMRI.jpg|thumb|right|400px|3D rendering of peak systolic CSF velocities in the aqueduct of Sylvius and 3rd ventricle obtained by 4D MRI imaging by [[Theresia Yiallourou]].]]-->
 
[[Image:banner.jpg|thumb|right|400px|''In silico'', ''in vivo'', and ''in vitro'' CSF experiments.  Laser Doppler vibrometry surface motion analysis of an in vitro spinal cord model (left), ''in vivo'' MR pulse wave velocity measurement in the spinal canal (center), and an ''in vitro'' cerebrospinal fluid system model (right).]]
 
  
 
== Welcome to the NIML==
 
== Welcome to the NIML==
The Neurophysiological Imaging and Modeling Laboratory (NIML) at The University of Idaho [http://www.uidaho.edu/cals/be Department of Biological Engineering] is led by Dr. [[Bryn Martin]].  We conduct clinical translational research to investigate the pathophysiology of central nervous system disorders and develop related medical technologies.  To help translate these findings and technologies to the clinic, we [[collaborators|collaborate]] with neurosurgeons, neurologists, neuroradiologists and medical device manufacturers.
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The Neurophysiological Imaging and Modeling Laboratory (NIML) at The University of Idaho [http://www.uidaho.edu/cals/be Department of Biological Engineering] is led by [[Bryn Martin]].  We conduct clinical translational research to investigate the pathophysiology of central nervous system (CNS) disorders and develop related medical technologies.   
 
 
'''IMPORTANT:  Dr. Martin is searching for a PhD/MS student to work on a [[Open Positions|NASA sponsored research project]] with a strong interest in imaging analysis and with good background in engineering, mathematics and programming skills.'''
 
 
 
== Research ==
 
  
Current NIML imaging and modeling focus topics include:  
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===Mission===
#Cerebrospinal fluid system physiology
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The mission of the NIML is to become an internationally recognized leader in the study of the cerebrospinal fluid (CSF) system in relation to neurological disorders and to contribute to the advancement of CSF related technologies through active transfer of our know-how to the clinic and to the medical technology sector.  Our multidisciplinary [[team]] and [[collaborators]] includes neurosurgeons, neurologists, neuroradiologists, engineers, artists, biologists and medical device manufacturers. Current research focus areas include:
 +
#CSF physiology, Chiari malformation & hydrocephalus
 
#Advanced MRI and ultrasound imaging and post-processing techniques
 
#Advanced MRI and ultrasound imaging and post-processing techniques
 
#Computational fluid dynamics simulation of biological flows
 
#Computational fluid dynamics simulation of biological flows
 
#Astronaut eye and brain biomechanics
 
#Astronaut eye and brain biomechanics
#Amyotrophic lateral sclerosis and Parkinson's
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#MRI-based Biomarkers for amyotrophic lateral sclerosis and Parkinson's  
#Chiari malformation and hydrocephalus
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#Intrathecal drug and gene vector delivery and CSF filtration (neurapheresis)
#Intrathecal drug and gene vector delivery
 
#Neuropheresis
 
 
#In vitro modeling  
 
#In vitro modeling  
#Virtual reality for medical applications  
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#Virtual reality for medical applications
  
=== Projects ===
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=== Research ===
Please click on the links below to learn more about the current, available, and past research projects at the NIML.
 
 
*[[Current projects]] that we are working on.
 
*[[Current projects]] that we are working on.
 
*[[Past projects]] that have been completed.
 
*[[Past projects]] that have been completed.
 
*[[Youtube videos]] of our research.
 
*[[Youtube videos]] of our research.
 +
*[https://scholar.google.com/citations?user=lcaLpj4AAAAJ&hl=en Publications] based on NIML research.
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*[[Background]] information on cerebrospinal fluid and the CNS.
  
=== Open Research Positions ===
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=== Team ===
The NIML is seeking to fill several [[Open Positions|Open Research Assistant Positions]].
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*[[Team]]   
 
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*[[Collaborators]]
=== Research Team ===
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* [[Open Positions|Open Research Assistant Positions]]
The NIML is a multi-disciplinary research group located at the University of Idaho and [[collaborators|collaborating institutions]]. 
 
*Click [[team|here]] to see our research team.  
 
*Click [[collaborators|here]] to see our collaborators.
 
 
 
=== Publications ===
 
*Click [https://scholar.google.com/citations?user=Nc4neIgAAAAJ&hl=en here] for a list of NIML publications on Google Scholar.
 
 
 
== NIML Facilities ==
 
Click [[NIML Facilities|here]] to see the NIML's research facilities. 
 
 
 
== Background ==
 
*Click [[background|here]] for background on neurophysiological imaging and modeling.
 
  
== Teaching ==
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=== Other Information ===
*Click [[courses|here]] for information on courses at University of Idaho related to Neural Engineering.
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*[[Information for New NIML Student Researchers]]
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*[[NIML Visitor Information| Visitor information]] including parking pass and directions.
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*[[NIML Facilities|Facilities]] available at the NIML.
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*[[NIML Meeting Schedule|Monthly lab meeting]]
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*[[Software]] that we use in the lab.
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*[[Courses]] related to Neural Engineering at University of Idaho.
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*[[Student Advising]]
  
 
== Links ==
 
== Links ==
*Click [[links| here]] for external links to related laboratories, conferences, and organizations.
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*[[Links]] to related laboratories, conferences, and organizations.
*Click [[software| here]] for external links to software that we use in our lab.
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*[http://illiad.lib.uidaho.edu/illiad/illiad.dll Iliad library loan system]
*Click [[NIML Visitor Information| here]] for NIML visitor information (parking / directions).
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*[https://help.uidaho.edu/ UIdaho Help System]
 
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*[https://transfer.ndc.nasa.gov/courier/web/1000@/wmLogin.html NASA NOMAD file transfer]
 
 
== NIML Events ==
 
*Click [[NIML Meeting Schedule|here]] for the NIML meeting schedule.
 
 
 
== News ==
 
 
 
{|class="wikitable sortable" | style="background: white; border: 0px solid rgb(153, 153, 153); align="left"; padding: 1em;" style="font-size: 100%;"
 
! align="center" width="150pt" | Date !! class="unsortable" align="left" | Announcement
 
|-
 
| 2016-10-14||
 
Congratulations to NIML Researchers [[Gabryel Conley]] and [[Tavara Freeman]] for being accepted to the [http://www.uidaho.edu/engr/degrees-and-programs/grand-challenges University of Idaho's Grand Challenges Program]!
 
|-
 
| 2016-09-16||
 
Deadline to signup for the [http://www.uidaho.edu/engr/degrees-and-programs/grand-challenges University of Idaho's Grand Challenges Program] is September 16, 2016.  
 
|-
 
|  2016-07-29 ||
 
Congratulations to NIML student [[Mohammadreza Khani]] on his abstract acceptance to the International Hydrocephalus and CSF Disorders Conference.
 
|-
 
|  2016-05-17 ||
 
Congratulations to NIML student [[Lucas Sass]] on his recent interview in the [http://www.uidaho.edu/news/news-articles/media-coverage/051916-engrgrad Moscow-Pullman Daily news].
 
|-
 
|  2016-05-13 ||
 
NIML welcomes our 2016 summer research students, [[Christina Gibbs]], [[Joshua Pluid]], [[Gabryel Conley]], [[Tavara Freeman]] and [[Violet Gomm]]. 
 
|-
 
|  2016-04-18 ||
 
Dr. [[Bryn Martin]], [[Brian Cleveley]] and [[Xing Tao]] received funding for their collaborative [https://www.uidaho.edu/news/news-articles/news-releases/2016-april/041816-vipwinners Vandal Ideas Project] grant.
 
|-
 
|  2016-04-07 ||
 
Congrats to ‪NIML researchers on their publication in the [http://link.springer.com/article/10.1007/s10439-016-1602-x?wt_mc=internal.event.1.SEM.ArticleAuthorOnlineFirst Annals of Biomedical Engineering]!
 
|-
 
|  2015-11-01 ||
 
Congratulations to NIML researchers their publication in the [http://link.springer.com/article/10.1007/s10439-015-1449-6 Journal of Biomechanics].
 
|}
 
 
 
== References ==
 
{{reflist}}
 

Revision as of 11:06, 14 August 2018

The University of Idaho NIML is located in Moscow, ID within the beautiful Palouse hills of the inland northwest!
MRI-based CFD simulation of CSF flow in a Chiari malformation patient by Soroush Pahlavian.
Computer simulation of intrathecal drug dispersion in the cervical spine of a nonhuman primate by Mohammadreza Khani.
A nonuniform deforming mesh simulation of cerebrospinal fluid flow in a non-human primate by Mohammadreza Khani.
Visualization of arachnoid trabeculae fibers with second harmonic generation (SHG), bright field and fluorescence with DAPI stain.
Pulsatile movement of cerebrospinal fluid around the spinal cord measured in an in vitro flow model by 4D Flow MRI.
Computational fluid dynamics simulation of CSF movement in the cervical spine by Soroush Pahlavian with spinal cord nerve roots and denticulate ligaments included.
3D printed eyeball and ocular nerve by Lucas Sass and Joshua Pluid.

Welcome to the NIML

The Neurophysiological Imaging and Modeling Laboratory (NIML) at The University of Idaho Department of Biological Engineering is led by Bryn Martin. We conduct clinical translational research to investigate the pathophysiology of central nervous system (CNS) disorders and develop related medical technologies.

Mission

The mission of the NIML is to become an internationally recognized leader in the study of the cerebrospinal fluid (CSF) system in relation to neurological disorders and to contribute to the advancement of CSF related technologies through active transfer of our know-how to the clinic and to the medical technology sector. Our multidisciplinary team and collaborators includes neurosurgeons, neurologists, neuroradiologists, engineers, artists, biologists and medical device manufacturers. Current research focus areas include:

  1. CSF physiology, Chiari malformation & hydrocephalus
  2. Advanced MRI and ultrasound imaging and post-processing techniques
  3. Computational fluid dynamics simulation of biological flows
  4. Astronaut eye and brain biomechanics
  5. MRI-based Biomarkers for amyotrophic lateral sclerosis and Parkinson's
  6. Intrathecal drug and gene vector delivery and CSF filtration (neurapheresis)
  7. In vitro modeling
  8. Virtual reality for medical applications

Research

Team

Other Information

Links