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== Welcome to the NIML ==
 
== Welcome to the NIML ==
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'''The Neurophysiological Imaging and Modeling Laboratory''' (NIML) at The University of Idaho [http://www.uidaho.edu/cals/bae Department of Biological Engineering] is led by Dr. [[Bryn Martin]]. Our aim is to conduct clinical translational research that enhances human health and well being for the millions of people affected by CNS disorders.  We develop and apply advanced MR imaging and computational modeling techniques to investigate the pathophysiology of CNS disorders and therapeutics from a '''hydrodynamic''' and '''biomechanical''' perspective and develop related medical technologies.
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'''The Neurophysiological Imaging and Modeling Laboratory''' (NIML) at The University of Idaho [http://www.uidaho.edu/cals/bae Department of Biological Engineering] is led by Dr. [[Bryn Martin]]. Our aim is to conduct clinical translational research that enhances human health and well being for the millions of people affected by CNS disorders.  We develop and apply advanced MR imaging and computational modeling techniques to investigate the pathophysiology of CNS disorders and therapeutics from a '''hydrodynamic''' and '''biomechanical''' perspective and develop related medical technologies.  For more background on neurophysiological imaging and modeling, click [background|here].  
  
 
=== Research team ===
 
=== Research team ===
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=== Publications ===
 
=== Publications ===
 
For a list of NIML publications at Google Scholar please click [https://scholar.google.com/citations?user=Nc4neIgAAAAJ&hl=en here].
 
For a list of NIML publications at Google Scholar please click [https://scholar.google.com/citations?user=Nc4neIgAAAAJ&hl=en here].
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== Backgroud ==
 
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[[Image:pulsatile.jpg|thumb|right|400px|Figure 5. Pulsatile movement of cerebrospinal fluid around the spinal cord at the second cervical vertebrae level in a healthy young subject image by [[Adrien Demuralt]].]]
 
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[[Image:cervical_spinal_subarachnoid_space.jpg|thumb|right|400px|Figure 6. Three-dimensional reconstruction of the cervical spinal subarachnoid space by [[Theresia Yiallourou]] without nerve roots included.  Reconstruction based on magnetic resonance images of the cervical spinal subarachnoid space conducted on a healthy young subject.]]
 
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===What is Neurophysiological Imaging and Modeling?===
 
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Click [[neurohydrodynamics|here]] for a presentation with background information on Neurophysiological Imaging and Modeling.
 
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'''[http://en.wikipedia.org/wiki/Neurohydrodynamics Neurohydrodynamics]''' is a division of [http://en.wikipedia.org/wiki/Neuroengineering neural engineering] that investigates the  [http://en.wikipedia.org/wiki/Hydrodynamics hydrodynamics] of the neurological system in health and disease.  It applies engineering principles and design concepts to neural engineering to help close the gap between [http://en.wikipedia.org/wiki/Fluid_mechanics fluid mechanics] and [http://en.wikipedia.org/wiki/Neurosurgical neurosurgical] and [http://en.wikipedia.org/wiki/Neurological neurological] [http://en.wikipedia.org/wiki/Medicine medicine].  Neurohydrodynamics combines fluid mechanics principles with [http://en.wikipedia.org/wiki/Neuroscience neuroscience] to help improve neurological disorder healthcare in terms of medical diagnosis, monitoring, and therapy. 
 
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===Key words=== 
 
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[http://en.wikipedia.org/wiki/Neurohydrodynamics Neurohydrodynamics], [http://en.wikipedia.org/wiki/Cerebrospinal_fluid cerebrospinal fluid], craniospinal disorders,  [http://en.wikipedia.org/wiki/Chiari_malformation chiari malformation], [http://en.wikipedia.org/wiki/Syringomyelia syringomyelia], [http://en.wikipedia.org/wiki/Hydrocephalus hydrocephalus], [http://en.wikipedia.org/wiki/Neural_drug_delivery_systems neural drug delivery], [http://en.wikipedia.org/wiki/Spinal_cord#Blood_supply spinal cord blood flow], [http://en.wikipedia.org/wiki/Cerebral_blood_flow cerebral blood flow], [http://en.wikipedia.org/wiki/Cerebral_perfusion_pressure cerebral perfusion and autoregulation], [http://en.wikipedia.org/wiki/Sleep_disorders sleep disorders], [http://en.wikipedia.org/wiki/Sleep_apnea sleep apnea], [http://en.wikipedia.org/wiki/Continuous_positive_airway_pressure continuous positive airway pressure], [http://en.wikipedia.org/wiki/Computational_fluid_dynamics computational fluid dynamics], [http://en.wikipedia.org/wiki/Magnetic_resonance_angiography MRI], 4DMRI and pcMRI, [http://en.wikipedia.org/wiki/Neuroengineering neuroengineering], [http://en.wikipedia.org/wiki/Neuroscience neuroscience], [http://en.wikipedia.org/wiki/Biomechanics#Biofluid_mechanics biofluid mechanics], [http://en.wikipedia.org/wiki/Neuroscience neuroscience], [http://en.wikipedia.org/wiki/Neuroengineering neuroengineering], [http://en.wikipedia.org/wiki/Medical_technology medical technology], [http://en.wikipedia.org/wiki/Neuromonitoring neuromonitoring].
 
  
 
== Links ==
 
== Links ==

Revision as of 18:19, 9 May 2016

Figure 1. Computational fluid dynamics simulation of CSF movement in the cervical spine by Soroush Pahlavian with spinal cord nerve roots and denticulate ligaments included.
Figure 2. 3D rendering of peak systolic CSF velocities in the aqueduct of Sylvius and 3rd ventricle obtained by 4D MRI imaging by Theresia Yiallourou.
Figure 3. in silico, in vivo, and in vitro CSF experiments. Laser Doppler vibrometry surface motion analysis of an in vitro spinal cord model (left), in vivo MR pulse wave velocity measurement in the spinal canal (center), and an in vitro cerebrospinal fluid system model (right).

Welcome to the NIML

The Neurophysiological Imaging and Modeling Laboratory (NIML) at The University of Idaho Department of Biological Engineering is led by Dr. Bryn Martin. Our aim is to conduct clinical translational research that enhances human health and well being for the millions of people affected by CNS disorders. We develop and apply advanced MR imaging and computational modeling techniques to investigate the pathophysiology of CNS disorders and therapeutics from a hydrodynamic and biomechanical perspective and develop related medical technologies. For more background on neurophysiological imaging and modeling, click [background|here].

Research team

Click here to learn more about open positions in the NIML. The NIML seeks highly motivated and critical-thinking students who wish to participate in a dynamic multi-disciplinary research team that makes new discoveries about CNS disorders using state-of-the-art medical imaging and modeling techniques. We are seeking motivated students for the fall 2015 semester at the University of Idaho, Department of Biological Engineering.

Research

Figure 4. Ongoing research projects at the Neurophysiological Imaging and Modeling Laboratory (NIML).

The NIML's conducts in vivo, in vitro and in silico experiments to investigate four main areas of research (Figure 4):

  1. Intrathecal drug and gene vector delivery
  2. Hydrocephalus and Chiari malformation
  3. Medical Devices and Technology
  4. Neurodegenerative disorders

Projects

Please click on the links below to learn more about the current, available, and past research projects at the NIML.

Publications

For a list of NIML publications at Google Scholar please click here.

Links

News

Date Announcement
2015-08-15

Update to be posted soon.

2015-08-??

Update to be posted soon.

References

Template:Reflist

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