Difference between revisions of "CSF lab.com"
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[[Image:banner.jpg|thumb|right|600px|''in silico'', ''in vivo'', and ''in vitro'' CSF experiments. Laser Doppler vibrometry surface motion analysis of an in vitro spinal cord model (left), ''in vivo'' MR pulse wave velocity measurement in the spinal canal (center), and an ''in vitro'' cerebrospinal fluid system model (right).]] | [[Image:banner.jpg|thumb|right|600px|''in silico'', ''in vivo'', and ''in vitro'' CSF experiments. Laser Doppler vibrometry surface motion analysis of an in vitro spinal cord model (left), ''in vivo'' MR pulse wave velocity measurement in the spinal canal (center), and an ''in vitro'' cerebrospinal fluid system model (right).]] | ||
− | [[Image:dist_csf.png|thumb|right| | + | [[Image:dist_csf.png|thumb|right|600px|Intracranial volumetric distribution of cerebrospinal fluid, blood, and brain parenchyma.]] |
− | [[Image:dist_vent.png|thumb|right| | + | [[Image:dist_vent.png|thumb|right|600px|Volumetric distribution of cerebrospinal fluid.]] |
= Overview = | = Overview = |
Revision as of 12:18, 17 December 2010
Welcome to the Cerebrospinal Fluid Laboratory wiki page.
Contents
Overview
The Cerebrospinal Fluid Laboratory is an international collaborative research site dedicated to investigation of the underlying biomechanical and hydrodynamic mechanisms responsible for pathologies of the cerebrospinal and cerebrovascular systems.
Purpose
- foster collaboration and discussion between cerebrospinal fluid and cerebrovascular researchers
- provide in vivo and in vitro experimental data to computational researchers
- increase interest in cerebrospinal fluid and craniospinal disorder research
Contact
- Please direct questions to: mail [atz] csflab [dotz] com.
Background information
Information on cerebrospinal fluid biomechanics from an anatomical and physiological perspective is provided.
Current projects
Visit the CSF lab Youtube channel to see some videos of our work [1].
CSF related
- Understanding the coupling of cranial blood flow and the cerebrospinal fluid system: an in vivo and in silico study
- What is the relative distribution of spinal subarachnoid space volumetric compliance in healthy subjects?
- Does CPAP influence cranial blood flow in healthy volunteers?
- Are changes in intracranial pressure detectable by measurement of the cerebrospinal fluid velocity wave speed in the spinal canal?
- in vitro and in silico modeling of CSF wave transmission in the spinal subarachnoid space
- An in vitro examination of the influence of spinal subarachnoid space shunting in post-traumatic syringomyelia
- How well do 3D CFD simulations compare with 4D MRI flow measurements?
- Finite element analysis of hydrocephalus: influence of heterogeneous cerebrospinal fluid content and anisotropic brain permeability
Cardiovascular related
- Computational modelling of the spinal cord blood supply
- 1-D computational modeling of the impact of aortic graft implantation
Available projects
Research related
- non-invasive assessment of local arterial compliance by simultaneous ultrasound and tonometry measurements
- Measurement and characterization of cough induced subarachnoid space pressure wave reverberations during lumbar puncture
Medical technology related
- non-invasive measurement of cerebrovascular properties
- a low-cost directional hearing aid
- design and development of an improved vascular graft
Past projects
- Quantification of the Modulus of Elasticity and Dynamic Properties of Sylgard for Various Mixing Ratios, 2003-2006
- MR Measurement of Cerebrospinal Fluid Velocity Wave Speed in the Spinal Canal
- Spinal Subarachnoid Space Pressure Measurements in an In Vitro Spinal Stenosis Model: Implications on Syringomyelia Theories
- The influence of coughing on cerebrospinal fluid pressure in an in vitro syringomyelia model with spinal subarachnoid space stenosis
- Syringomyelia Hydrodynamics: An In Vitro Study Based on In Vivo Measurements
External links
Cerebrospinal Fluid Research Laboratories
- EPFL Hemodynamics and Cardiovascular Technology Lab
- University of Akron Biofluids Lab
- ETH smart shunt hydrocephalus project
- Fluidics and Biocomplexity Group
- Research Group Multimodal Analysis of Brain Function
- Laboratory of Product and Process Design
Lymphatic Research Laboratories
Vascular Research Laboratories
- University of Illinois at Chicago Acoustics and Vibrations Lab
- CMU Vascular Biomechanics Lab
- UPitt Engineered Tissue Mechanics and Mechanobiology Lab
- UPitt Vascular Bioengineering Lab
Organizations and foundations
- Conquer Chiari.org
- American Syringomyelia Alliance Project
- Column of Hope
- Chiari Syringomyelia Foundation
Societies
- International Society for Cerebral Blood Flow and Metabolism
- Society for Research into Hydrocephalus and Spina Bifida
Related conferences
- ICP 2010
- Syringomyelia 2010
- International society for hydrocephalus and cerebrospinal fluid disorders
- International symposium on cerebral blood flow, metabolism and function
- Conquer chiari research conference
- American Clinical Neurophysiology Society