CSF lab.com

Welcome to the Cerebrospinal Fluid Laboratory wiki page.

Overview

The Cerebrospinal Fluid Laboratory is dedicated to investigation of the underlying biomechanical and hydrodynamic mechanisms responsible for pathologies of the cerebrospinal and cerebrovascular systems.

Purpose

• foster collaboration and discussion between cerebrospinal fluid and cerebrovascular researchers
• provide in vivo and in vitro experimental data to computational researchers
• increase interest in cerebrospinal fluid research

Projects

Active

• cerebral blood flow and cerebrospinal fluid pulsation coupling
• What is the relative distribution of spinal subarachnoid space volumetric compliance in healthy subjects?
• Does CPAP influence cranial blood flow in healthy volunteers?
• Are changes in intracranial pressure detectable by measurement of the cerebrospinal fluid velocity wave speed in the spinal canal?
• in vitro and in silico modeling of CSF wave transmission in the spinal subarachnoid space
• syringomyelia and Chiari malformation

Past

• Quantification of the Modulus of Elasticity and Dynamic Properties of Sylgard for Various Mixing Ratios, 2003-2006

Available projects for masters students

• design and development of an improved vascular graft
• implementation of a 4DMR flow sequence

External Links

Research laboratories

• EPFL Hemodynamics and Cardiovascular Technology Lab
• University of Akron Biofluids Lab
• University of Illinois at Chicago Acoustics and Vibrations Lab
• CMU Vascular Biomechanics Lab
• UPitt Engineered Tissue Mechanics and Mechanobiology Lab
• UPitt Vascular Bioengineering Lab
• ETH measurement and control laboratory
• ETH smart shunt hydrocephalus project
• ETH laboratory of thermodynamics in emerging technologies

Organizations

• Conquer Chiari.org
• American Syringomyelia Alliance Project
• Column of Hope
• Chiari Syringomyelia Foundation
• ASME
• BMES News Bulletin
• National Kidney Foundation
• Whitaker Foundation
• NIH Search for Grants CRISP