Difference between revisions of "CSF lab.com"

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<big>'''Welcome to the Cerebrospinal Fluid Laboratory wiki page.'''</big>
 
 
 
[[Image:banner.jpg|thumb|right|400px|''in silico'', ''in vivo'', and ''in vitro'' CSF experiments.  Laser Doppler vibrometry surface motion analysis of an in vitro spinal cord model (left), ''in vivo'' MR pulse wave velocity measurement in the spinal canal (center), and an ''in vitro'' cerebrospinal fluid system model (right).]]
 
[[Image:banner.jpg|thumb|right|400px|''in silico'', ''in vivo'', and ''in vitro'' CSF experiments.  Laser Doppler vibrometry surface motion analysis of an in vitro spinal cord model (left), ''in vivo'' MR pulse wave velocity measurement in the spinal canal (center), and an ''in vitro'' cerebrospinal fluid system model (right).]]
  
[[Image:dist_csf.png|thumb|right|400px|Intracranial volumetric distribution of cerebrospinal fluid, blood, and brain parenchyma.]]
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= Overview =
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Welcome to the Cerebrospinal Fluid (CSF) Laboratory research website!  The CSF Lab is led by [[Bryn Martin]] in conjunction with the [[Laboratory of Hemodynamics and Cardiovascular Technology]] at the Swiss Federal Institute of Technology (EPFL) to investigate the underlying '''biomechanical''' and '''hydrodynamic''' mechanisms responsible for pathologies of the cerebrospinal and cerebrovascular systems. Please direct questions to [[Bryn Martin]] at: mail [atz] csflab [dotz] com.
  
[[Image:dist_vent.png|thumb|right|400px|Volumetric distribution of cerebrospinal fluid.]]
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'''Purpose of CSF lab.com'''
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# '''foster''' collaboration and discussion between CSF and cerebrovascular researchers
 +
# '''provide''' in vivo and in vitro experimental data
 +
# '''increase''' interest in CSF and craniospinal disorder research
  
== Overview ==
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''' Key words '''
The Cerebrospinal Fluid Laboratory is a collaborative research site dedicated to investigation of the underlying '''biomechanical''' and '''hydrodynamic''' mechanisms responsible for pathologies of the cerebrospinal and cerebrovascular systems.  
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Neurohydrodynamics, cerebrospinal fluid, craniospinal disorders, chiari malformation, syringomyelia, hydrocephalus, spinal drug delivery, spinal cord blood flow, cerebral blood flow, cerebral autoregulation, sleep disorders, sleep apnea, continuous positive airway pressure, computational fluid dynamics, 4DMRI, neuroengineering, neuroscience,
  
'''Purpose'''
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''' Background information on neurohydrodynamics'''
# '''foster''' collaboration and discussion between cerebrospinal fluid and cerebrovascular researchers
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Information on [[cerebrospinal fluid biomechanics]] from an anatomical and physiological perspective is provided.
# '''provide''' in vivo and in vitro experimental data to computational researchers
 
# '''increase''' interest in cerebrospinal fluid and craniospinal disorder research
 
  
''' Contact'''
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= Available projects for Ph.D., M.S. or B.S. students (semester or thesis)=
:Please direct questions to [[Bryn Martin]] at: mail [atz] csflab [dotz] com.
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'''Cerebrospinal fluid related'''
 +
*[[Measurement of brain volume change due to acute modification of intracranial pressure]]
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*[[Construction and MRI testing of a 3D model of the spinal subarachnoid space]]
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*[[Measurement and characterization of cough induced subarachnoid space pressure wave reverberations during lumbar puncture]]
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*[[What is the relative distribution of spinal subarachnoid space volumetric compliance in healthy subjects?]]
 +
 
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'''Sleep and breathing related'''
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*[[Physiological impact of continuous positive airway pressure (CPAP) on cerebral blood flow and cerebrospinal fluid dynamics in healthy awake volunteers (MRI)]]
 +
 
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'''Cardiovascular related'''
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*[[A prospective and controlled clinical study to evaluate the effect of ascending aortic reconstructive surgery on cardiovascular hemodynamics]]
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*[[non-invasive measurement of cerebrovascular properties]]
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*[[design and development of an improved vascular graft]]
  
== Background information ==
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'''Technology related'''
Information on [[cerebrospinal fluid biomechanics]] from an anatomical and physiological perspective is provided.
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*[[a low-cost directional hearing aid]]
  
== Current projects ==
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= Current projects =
 
Visit the CSF lab Youtube channel to see some videos of our work [http://www.youtube.com/user/csflab].
 
Visit the CSF lab Youtube channel to see some videos of our work [http://www.youtube.com/user/csflab].
  
 
'''CSF related'''
 
'''CSF related'''
 
*[[Understanding the coupling of cranial blood flow and the cerebrospinal fluid system: an in vivo and in silico study]]
 
*[[Understanding the coupling of cranial blood flow and the cerebrospinal fluid system: an in vivo and in silico study]]
*[[What is the relative distribution of spinal subarachnoid space volumetric compliance in healthy subjects?]]
 
 
*[[Physiological impact of continuous positive airway pressure (CPAP) on total cerebral blood flow in healthy awake volunteers (ultrasound study)]]
 
*[[Physiological impact of continuous positive airway pressure (CPAP) on total cerebral blood flow in healthy awake volunteers (ultrasound study)]]
 
*[[Are changes in intracranial pressure detectable by measurement of the cerebrospinal fluid velocity wave speed in the spinal canal?]]
 
*[[Are changes in intracranial pressure detectable by measurement of the cerebrospinal fluid velocity wave speed in the spinal canal?]]
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'''Cardiovascular related'''
 
'''Cardiovascular related'''
 
*[[1-D computational modeling of the impact of aortic graft implantation]]
 
*[[1-D computational modeling of the impact of aortic graft implantation]]
*[[In vivo measurement of pressure and flow in aortic graft recipients]]
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*[[A prospective and controlled clinical study to evaluate the effect of ascending aortic reconstructive surgery on cardiovascular hemodynamics]]
 
 
= Available projects =
 
'''Research related'''
 
*[[non-invasive assessment of local arterial compliance by simultaneous ultrasound and tonometry measurements]]
 
*[[Measurement and characterization of cough induced subarachnoid space pressure wave reverberations during lumbar puncture]]
 
 
 
'''Medical technology related'''
 
*[[non-invasive measurement of cerebrovascular properties]]
 
*[[a low-cost directional hearing aid]]
 
*[[design and development of an improved vascular graft]]
 
  
== Past projects ==
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= Past projects =
 
*[[Quantification of the Modulus of Elasticity and Dynamic Properties of Sylgard for Various Mixing Ratios, 2003-2006]]
 
*[[Quantification of the Modulus of Elasticity and Dynamic Properties of Sylgard for Various Mixing Ratios, 2003-2006]]
 
*[[MR Measurement of Cerebrospinal Fluid Velocity Wave Speed in the Spinal Canal]]
 
*[[MR Measurement of Cerebrospinal Fluid Velocity Wave Speed in the Spinal Canal]]
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*[[Syringomyelia Hydrodynamics: An In Vitro Study Based on In Vivo Measurements]]
 
*[[Syringomyelia Hydrodynamics: An In Vitro Study Based on In Vivo Measurements]]
  
== External links ==
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= External links =
 
'''Cerebrospinal Fluid Research Laboratories'''
 
'''Cerebrospinal Fluid Research Laboratories'''
 
:[http://lhtc.epfl.ch/ EPFL Hemodynamics and Cardiovascular Technology Lab]
 
:[http://lhtc.epfl.ch/ EPFL Hemodynamics and Cardiovascular Technology Lab]
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:[http://www.acns.org/ American Clinical Neurophysiology Society]
 
:[http://www.acns.org/ American Clinical Neurophysiology Society]
  
== References ==
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= References =
 
{{reflist}}
 
{{reflist}}

Latest revision as of 10:50, 20 July 2011

in silico, in vivo, and in vitro CSF experiments. Laser Doppler vibrometry surface motion analysis of an in vitro spinal cord model (left), in vivo MR pulse wave velocity measurement in the spinal canal (center), and an in vitro cerebrospinal fluid system model (right).

Overview

Welcome to the Cerebrospinal Fluid (CSF) Laboratory research website! The CSF Lab is led by Bryn Martin in conjunction with the Laboratory of Hemodynamics and Cardiovascular Technology at the Swiss Federal Institute of Technology (EPFL) to investigate the underlying biomechanical and hydrodynamic mechanisms responsible for pathologies of the cerebrospinal and cerebrovascular systems. Please direct questions to Bryn Martin at: mail [atz] csflab [dotz] com.

Purpose of CSF lab.com

  1. foster collaboration and discussion between CSF and cerebrovascular researchers
  2. provide in vivo and in vitro experimental data
  3. increase interest in CSF and craniospinal disorder research

Key words Neurohydrodynamics, cerebrospinal fluid, craniospinal disorders, chiari malformation, syringomyelia, hydrocephalus, spinal drug delivery, spinal cord blood flow, cerebral blood flow, cerebral autoregulation, sleep disorders, sleep apnea, continuous positive airway pressure, computational fluid dynamics, 4DMRI, neuroengineering, neuroscience,

Background information on neurohydrodynamics Information on cerebrospinal fluid biomechanics from an anatomical and physiological perspective is provided.

Available projects for Ph.D., M.S. or B.S. students (semester or thesis)

Cerebrospinal fluid related

Sleep and breathing related

Cardiovascular related

Technology related

Current projects

Visit the CSF lab Youtube channel to see some videos of our work [1].

CSF related

Cardiovascular related

Past projects

External links

Cerebrospinal Fluid Research Laboratories

EPFL Hemodynamics and Cardiovascular Technology Lab
University of Akron Biofluids Lab
ETH smart shunt hydrocephalus project
Fluidics and Biocomplexity Group
Research Group Multimodal Analysis of Brain Function
Laboratory of Product and Process Design

Lymphatic Research Laboratories

Lymphatic Research Group at Sunnybrook Toronto

Vascular Research Laboratories

University of Illinois at Chicago Acoustics and Vibrations Lab
CMU Vascular Biomechanics Lab
UPitt Engineered Tissue Mechanics and Mechanobiology Lab
UPitt Vascular Bioengineering Lab

Organizations and foundations

Conquer Chiari.org
American Syringomyelia Alliance Project
Column of Hope
Chiari Syringomyelia Foundation

Societies

International Society for Cerebral Blood Flow and Metabolism
Society for Research into Hydrocephalus and Spina Bifida

Related conferences

ICP 2010
Syringomyelia 2010
International society for hydrocephalus and cerebrospinal fluid disorders
International symposium on cerebral blood flow, metabolism and function
Conquer chiari research conference
American Clinical Neurophysiology Society

References

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