Difference between revisions of "CSF lab.com"
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[[Image:banner.jpg|thumb|right|400px|''in silico'', ''in vivo'', and ''in vitro'' CSF experiments. Laser Doppler vibrometry surface motion analysis of an in vitro spinal cord model (left), ''in vivo'' MR pulse wave velocity measurement in the spinal canal (center), and an ''in vitro'' cerebrospinal fluid system model (right).]] | [[Image:banner.jpg|thumb|right|400px|''in silico'', ''in vivo'', and ''in vitro'' CSF experiments. Laser Doppler vibrometry surface motion analysis of an in vitro spinal cord model (left), ''in vivo'' MR pulse wave velocity measurement in the spinal canal (center), and an ''in vitro'' cerebrospinal fluid system model (right).]] | ||
= Overview = | = Overview = | ||
− | The Cerebrospinal Fluid Laboratory is a collaborative research site dedicated to investigation of the underlying '''biomechanical''' and '''hydrodynamic''' mechanisms responsible for pathologies of the cerebrospinal and cerebrovascular systems. | + | Welcome to the Cerebrospinal Fluid Laboratory wiki page! The Cerebrospinal Fluid Laboratory is a collaborative research site led by [[Bryn Martin]] that is dedicated to investigation of the underlying '''biomechanical''' and '''hydrodynamic''' mechanisms responsible for pathologies of the cerebrospinal and cerebrovascular systems. |
'''Purpose''' | '''Purpose''' |
Revision as of 15:30, 19 July 2011
Contents
Overview
Welcome to the Cerebrospinal Fluid Laboratory wiki page! The Cerebrospinal Fluid Laboratory is a collaborative research site led by Bryn Martin that is dedicated to investigation of the underlying biomechanical and hydrodynamic mechanisms responsible for pathologies of the cerebrospinal and cerebrovascular systems.
Purpose
- foster collaboration and discussion between cerebrospinal fluid and cerebrovascular researchers
- provide in vivo and in vitro experimental data to computational researchers
- increase interest in cerebrospinal fluid and craniospinal disorder research
Contact
- Please direct questions to Bryn Martin at: mail [atz] csflab [dotz] com.
Background information
Information on cerebrospinal fluid biomechanics from an anatomical and physiological perspective is provided.
Available projects for Ph.D., M.S. or B.S. students (semester or thesis)
Research related
- Physiological impact of continuous positive airway pressure (CPAP) on cerebral blood flow and cerebrospinal fluid dynamics in healthy awake volunteers (MRI)
- Measurement of brain volume change due to acute modification of intracranial pressure
- Construction and MRI testing of a 3D model of the spinal subarachnoid space
- Measurement and characterization of cough induced subarachnoid space pressure wave reverberations during lumbar puncture
Medical technology related
- non-invasive measurement of cerebrovascular properties
- a low-cost directional hearing aid
- design and development of an improved vascular graft
Current projects
Visit the CSF lab Youtube channel to see some videos of our work [1].
CSF related
- Understanding the coupling of cranial blood flow and the cerebrospinal fluid system: an in vivo and in silico study
- What is the relative distribution of spinal subarachnoid space volumetric compliance in healthy subjects?
- Physiological impact of continuous positive airway pressure (CPAP) on total cerebral blood flow in healthy awake volunteers (ultrasound study)
- Are changes in intracranial pressure detectable by measurement of the cerebrospinal fluid velocity wave speed in the spinal canal?
- in vitro and in silico modeling of CSF wave transmission in the spinal subarachnoid space
- An in vitro examination of the influence of spinal subarachnoid space shunting in post-traumatic syringomyelia
- How well do 3D CFD simulations compare with 4D MRI flow measurements in the third ventricle?
- Finite element analysis of hydrocephalus: influence of heterogeneous cerebrospinal fluid content and anisotropic brain permeability
Cardiovascular related
- 1-D computational modeling of the impact of aortic graft implantation
- In vivo measurement of pressure and flow in aortic graft recipients
Past projects
- Quantification of the Modulus of Elasticity and Dynamic Properties of Sylgard for Various Mixing Ratios, 2003-2006
- MR Measurement of Cerebrospinal Fluid Velocity Wave Speed in the Spinal Canal
- Spinal Subarachnoid Space Pressure Measurements in an In Vitro Spinal Stenosis Model: Implications on Syringomyelia Theories
- The influence of coughing on cerebrospinal fluid pressure in an in vitro syringomyelia model with spinal subarachnoid space stenosis
- Syringomyelia Hydrodynamics: An In Vitro Study Based on In Vivo Measurements
External links
Cerebrospinal Fluid Research Laboratories
- EPFL Hemodynamics and Cardiovascular Technology Lab
- University of Akron Biofluids Lab
- ETH smart shunt hydrocephalus project
- Fluidics and Biocomplexity Group
- Research Group Multimodal Analysis of Brain Function
- Laboratory of Product and Process Design
Lymphatic Research Laboratories
Vascular Research Laboratories
- University of Illinois at Chicago Acoustics and Vibrations Lab
- CMU Vascular Biomechanics Lab
- UPitt Engineered Tissue Mechanics and Mechanobiology Lab
- UPitt Vascular Bioengineering Lab
Organizations and foundations
- Conquer Chiari.org
- American Syringomyelia Alliance Project
- Column of Hope
- Chiari Syringomyelia Foundation
Societies
- International Society for Cerebral Blood Flow and Metabolism
- Society for Research into Hydrocephalus and Spina Bifida
Related conferences
- ICP 2010
- Syringomyelia 2010
- International society for hydrocephalus and cerebrospinal fluid disorders
- International symposium on cerebral blood flow, metabolism and function
- Conquer chiari research conference
- American Clinical Neurophysiology Society