CSF lab.com
From niml.org
Welcome to the Cerebrospinal Fluid Laboratory wiki page.
Contents
Overview
The Cerebrospinal Fluid Laboratory is a collaborative research site dedicated to investigation of the underlying biomechanical and hydrodynamic mechanisms responsible for pathologies of the cerebrospinal and cerebrovascular systems.
Purpose
- foster collaboration and discussion between cerebrospinal fluid and cerebrovascular researchers
- provide in vivo and in vitro experimental data to computational researchers
- increase interest in cerebrospinal fluid and craniospinal disorder research
Contact
- Please direct questions to Bryn Martin at: mail [atz] csflab [dotz] com.
Background information
Information on cerebrospinal fluid biomechanics from an anatomical and physiological perspective is provided.
Current projects
Visit the CSF lab Youtube channel to see some videos of our work [1].
CSF related
- Understanding the coupling of cranial blood flow and the cerebrospinal fluid system: an in vivo and in silico study
- What is the relative distribution of spinal subarachnoid space volumetric compliance in healthy subjects?
- Physiological impact of continuous positive airway pressure (CPAP) on total cerebral blood flow in healthy awake volunteers (ultrasound study)
- Are changes in intracranial pressure detectable by measurement of the cerebrospinal fluid velocity wave speed in the spinal canal?
- in vitro and in silico modeling of CSF wave transmission in the spinal subarachnoid space
- An in vitro examination of the influence of spinal subarachnoid space shunting in post-traumatic syringomyelia
- How well do 3D CFD simulations compare with 4D MRI flow measurements in the third ventricle?
- Finite element analysis of hydrocephalus: influence of heterogeneous cerebrospinal fluid content and anisotropic brain permeability
Cardiovascular related
- 1-D computational modeling of the impact of aortic graft implantation
- In vivo measurement of pressure and flow in aortic graft recipients
Available projects for Ph.D., M.S. or B.S. students (semester or thesis projects)
Research related
- non-invasive assessment of local arterial compliance by simultaneous ultrasound and tonometry measurements
- Measurement and characterization of cough induced subarachnoid space pressure wave reverberations during lumbar puncture
- Physiological impact of continuous positive airway pressure (CPAP) on cerebral blood flow and cerebrospinal fluid dynamics in healthy awake volunteers (MRI)
Medical technology related
- non-invasive measurement of cerebrovascular properties
- a low-cost directional hearing aid
- design and development of an improved vascular graft
Past projects
- Quantification of the Modulus of Elasticity and Dynamic Properties of Sylgard for Various Mixing Ratios, 2003-2006
- MR Measurement of Cerebrospinal Fluid Velocity Wave Speed in the Spinal Canal
- Spinal Subarachnoid Space Pressure Measurements in an In Vitro Spinal Stenosis Model: Implications on Syringomyelia Theories
- The influence of coughing on cerebrospinal fluid pressure in an in vitro syringomyelia model with spinal subarachnoid space stenosis
- Syringomyelia Hydrodynamics: An In Vitro Study Based on In Vivo Measurements
External links
Cerebrospinal Fluid Research Laboratories
- EPFL Hemodynamics and Cardiovascular Technology Lab
- University of Akron Biofluids Lab
- ETH smart shunt hydrocephalus project
- Fluidics and Biocomplexity Group
- Research Group Multimodal Analysis of Brain Function
- Laboratory of Product and Process Design
Lymphatic Research Laboratories
Vascular Research Laboratories
- University of Illinois at Chicago Acoustics and Vibrations Lab
- CMU Vascular Biomechanics Lab
- UPitt Engineered Tissue Mechanics and Mechanobiology Lab
- UPitt Vascular Bioengineering Lab
Organizations and foundations
- Conquer Chiari.org
- American Syringomyelia Alliance Project
- Column of Hope
- Chiari Syringomyelia Foundation
Societies
- International Society for Cerebral Blood Flow and Metabolism
- Society for Research into Hydrocephalus and Spina Bifida
Related conferences
- ICP 2010
- Syringomyelia 2010
- International society for hydrocephalus and cerebrospinal fluid disorders
- International symposium on cerebral blood flow, metabolism and function
- Conquer chiari research conference
- American Clinical Neurophysiology Society